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COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. This report highlights the major achievements of EU-ROS as well as research updates and new perspectives arising from its members. The EU-ROS consortium comprised more than 140 active members who worked together for four years on the topics briefly described below. The formation of reactive oxygen and nitrogen species (RONS) is an established hallmark of our aerobic environment and metabolism but RONS also act as messengers via redox regulation of essential cellular processes. The fact that many diseases have been found to be associated with oxidative stress established the theory of oxidative stress as a trigger of diseases that can be corrected by antioxidant therapy. 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Diseases","subTitle":null,"descriptions":["The monoaminergic systems are the target of several drugs for the treatment of mood, motor and cognitive disorders as well as neurological conditions.In most cases, advances have occurred through serendipity, except for Parkinson’s disease where the pathophysiology led almost immediately to the introduction of dopamine restoring agents. Extensive neuropharmacological studies first showed that the primary target of antipsychotics, antidepressants, and anxiolytic drugs were specific components of the monoaminergic systems.Later, some dramatic side effects associated with older medicines were shown to disappear with new chemical compounds targeting the origin of the therapeutic benefit more specifically.The increased knowledge regarding the function and interaction of the monoaminergic systems in the brain resulting from in vivo neurochemical and neurophysiological studies indicated new monoaminergic targets that could achieve the efficacy of the older medicines with fewer side effects. Yet, this accumulated knowledge regarding monoamines did not produce valuable strategies for diseases where no monoaminergic drug has been shown to be effective.Here, we emphasize the new therapeutic and monoaminergic-based strategies for the treatment of psychiatric diseases.We will consider three main groups of diseases, based on the evidence of monoamines involvement(schizophrenia, depression, obesity), t he identification of monoamines in the diseases processes (Parkinson’s disease, addiction) and the prospect of the involvement of monoaminergic mechanisms(epilepsy, Alzheimer’s disease, stroke).In most cases, the clinically available monoaminergic drugs induce wide spread modifications of amine tone or excitability through neurobiological networks and exemplify the overlap between therapeutic approaches to psychiatric and neurological conditions. 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They are predominantly produced by fungi of the genus Aspergillus, series Versicolores. The presence of these mycotoxins was investigated in indoor environments, while the data regarding food products remains insufficient, especially for 5-M-STC. Given the high consumption of beer in Croatia and the world, the presence of STC and 5-M-STC in beer may negatively affect the health of exposed individuals. Thus, 58 different samples of beer were collected from the Croatian market, extracted by combining the QuEChERS (Quick Easy Cheap Effective Rugged Safe) extraction procedure and dispersive solid phase extraction (dSPE). The prepared extracts were analysed by thin-layer chromatography (TLC) using silica gel 60 as a stationary phase and toulen:ethyl acetate:formic acid 90 vol. % (5:4:1) as a mobile phase. Following chromatographic separation, to enhance the detection of the fluorescent spots assigned to STC and 5-M-STC, the TLC plates were dried and heated for 10 minutes in an oven at 140 °C. Additionally, the TLC plates were sprayed with aluminium chloride solution prepared in ethanol 60 vol. %. The limit of detection (LOD) was 1.3 μg/mL for STC and 3.2 μg/mL for 5-M-STC. While STC was not detected in any of the samples, 5-M-STC was detected in 46.55% of the samples. The presence of 5-M-STC was confirmed by UV-Vis spectroscopy following the extraction of the spot of interest from the TLC plate. Further analysis of the same extracts by application of more sensitive chromatographic techniques will allow for a more accurate interpretation of these observations, allow the detection of STC and 5-M-STC in the concentrations below the LOD, and enable us to quantify both metabolites."],"publicationDate":"2022-01-01","publisher":null,"embargoEndDate":null,"sources":null,"formats":null,"contributors":["Šegvić Klarić, M.","Rašić, D."],"coverages":null,"bestAccessRight":{"code":"c_abf2","label":"OPEN","scheme":"http://vocabularies.coar-repositories.org/documentation/access_rights/"},"container":null,"documentationUrls":null,"codeRepositoryUrl":null,"programmingLanguage":null,"contactPeople":null,"contactGroups":null,"tools":null,"size":null,"version":null,"geoLocations":null,"id":"57a035e5b1ae::95df25270438d5831dbc45444c4c612d","originalIds":["50|57a035e5b1ae::95df25270438d5831dbc45444c4c612d","1269862"],"pids":null,"dateOfCollection":null,"lastUpdateTimeStamp":null,"indicators":{"citationImpact":{"citationCount":0.0,"influence":2.1921431E-9,"popularity":1.4877204E-9,"impulse":0.0,"citationClass":"C5","influenceClass":"C5","impulseClass":"C5","popularityClass":"C5"}},"projects":[{"id":"mestd_______::bc91657886fe33aff1919bdeb1a4ef96","code":"200222","acronym":null,"title":"Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200222 (Institute for Food Technology, Novi Sad)","funder":"Ministry of Education, Science and Technological Development of Republic of Serbia","pids":null},{"id":"corda__h2020::d28d0653371ce05d4504dd91e542176f","code":"754380","acronym":"ResearchLeaders2025","title":"Research Leaders 2025 - 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Good health"},"provenance":null}],"mainTitle":"Assisted reproductive technology techniques and risk for neurodevelopmental disorders","subTitle":null,"descriptions":["Assisted reproductive technology (ART) techniques are becoming more common nowadays, due to the growing incidence of infertility. Such pregnancies are more often multiple, which carries the risk of premature birth and lower birth weight and, accordingly, a higher risk of occurrence of neurodevelop mental disorders. Aside from the before mentioned, other known risk factors for neurodevelopmental disorders include chorioamnionitis, gestational diabetes, and respiratory distress. The aim of the study was to compare the prevalence of risk factors for neurodevelopmental disorders between two groups of children born preterm, those conceived through ART and those conceived naturally. This was a retrospective study based on the data of births collected by Croatian Institute of Public Health for the year 2018. The study included a total of 2233 children born before week 37 of gestational age, 181 of which were conceived through ART. The prevalence of pathological con ditions during pregnancy, delivery, and at birth, known as neurodevelopmental risk factors, was compared between children conceived through ART and those conceived natu rally. The Mann-Whitney U test was used to perform data analysis. Pathological conditions in pregnancy were recorded in 82.3% of children conceived by ART, compared to 58.4% of children conceived naturally (p <0.001). The most common disorders during pregnancy are twin pregnancy (2.8%), cho rioamnionitis (2.8%), and retarded fetal growth (2.8%). On the other hand, in the group of naturally conceived neonates, the most common diagnoses were retarded fetal growth (3.5%) and gestational diabetes (3.0%). It was observed that the share of children with pathological conditions was significantly higher in the group of those con ceived by ART (92.2%) compared to the second group (84.1%) of children (p = 0.003). The diagnoses that predomi nated among the ART conceived after delivery were neonatal respiratory arrest (24.9%) and low birth weight (14.9%). Additionally, the mean birth weight was significantly lower in the group of children conceived by ART (2170.77 grams), in comparison to another group (2307.68 grams, p=0.015). Nevertheless, groups of neonates did not differ significantly in postnatal mortality (p = 1.00). Newborns conceived by ART are more likely to suffer from conditions that represent risk for factors for neurodevelopmen tal disorders. Neonatal respiratory arrest especially represents the risk for the neurodevelopmental disorders. The results of this research are consistent with other published studies, further research is needed to assess other risk factors associated with ART."],"publicationDate":"2021-01-01","publisher":null,"embargoEndDate":null,"sources":null,"formats":null,"contributors":null,"coverages":null,"bestAccessRight":{"code":"c_14cb","label":"CLOSED","scheme":"http://vocabularies.coar-repositories.org/documentation/access_rights/"},"container":null,"documentationUrls":null,"codeRepositoryUrl":null,"programmingLanguage":null,"contactPeople":null,"contactGroups":null,"tools":null,"size":null,"version":null,"geoLocations":null,"id":"57a035e5b1ae::9783004f2314f356cbaf357e5c5c59e1","originalIds":["50|57a035e5b1ae::9783004f2314f356cbaf357e5c5c59e1","1194880"],"pids":null,"dateOfCollection":null,"lastUpdateTimeStamp":null,"indicators":{"citationImpact":{"citationCount":0.0,"influence":2.1921431E-9,"popularity":1.2948822E-9,"impulse":0.0,"citationClass":"C5","influenceClass":"C5","impulseClass":"C5","popularityClass":"C5"}},"projects":null,"organizations":[{"legalName":"University College Cork","acronym":"UCC","id":"openorgs____::b8b8ca674452579f3f593d9f5e557483","pids":[{"scheme":"Wikidata","value":"Q16902157"},{"scheme":"fundref","value":"501100001636"},{"scheme":"mag_id","value":"27577105"},{"scheme":"ISNI","value":"0000000123318773"},{"scheme":"PIC","value":"999975717"},{"scheme":"OrgRef","value":"738094"},{"scheme":"Wikidata","value":"Q1574185"},{"scheme":"OrgReg","value":"IE0002"},{"scheme":"FundRef","value":"501100001636"},{"scheme":"GRID","value":"grid.7872.a"},{"scheme":"wikidata","value":"Q16902157"},{"scheme":"ROR","value":"https://ror.org/03265fv13"},{"scheme":"wikidata","value":"Q1574185"}]},{"legalName":"Cork University Hospital","acronym":"CUH","id":"openorgs____::84885b8b6d48f4d1aea97393b65d0b5b","pids":[{"scheme":"wikidata","value":"Q5170825"},{"scheme":"Wikidata","value":"Q5170825"},{"scheme":"OrgReg","value":"IE2003"},{"scheme":"ISNI","value":"0000000406176269"},{"scheme":"ROR","value":"https://ror.org/04q107642"},{"scheme":"mag_id","value":"2802396013"},{"scheme":"GRID","value":"grid.411916.a"},{"scheme":"OrgRef","value":"27989367"}]},{"legalName":"Health Service Executive","acronym":"Health Service Executive","id":"openorgs____::9b3fd02daf7da98893cd93dfbc557b71","pids":[{"scheme":"OrgRef","value":"4017657"},{"scheme":"FundRef","value":"100018270"},{"scheme":"fundref","value":"100018270"},{"scheme":"wikidata","value":"Q5690681"},{"scheme":"PIC","value":"993521919"},{"scheme":"GRID","value":"grid.424617.2"},{"scheme":"ROR","value":"https://ror.org/04zke5364"},{"scheme":"mag_id","value":"37076085"},{"scheme":"Wikidata","value":"Q5690681"}]}],"communities":null,"collectedFrom":[{"key":"openaire____::345c9d171ef3c5d706d08041d506428c","value":"Croatian Scientific Bibliography - CROSBI"}],"instances":[{"alternateIdentifiers":[{"scheme":"doi","value":"10.1136/archdischild-2021-europaediatrics.475"}],"accessRight":{"code":"c_14cb","label":"CLOSED","scheme":"http://vocabularies.coar-repositories.org/documentation/access_rights/","openAccessRoute":null},"type":"Conference object","urls":["https://doi.org/10.1136/archdischild-2021-europaediatrics.475","https://www.bib.irb.hr/1194880"],"publicationDate":"2021-01-01","refereed":"nonPeerReviewed","hostedBy":{"key":"openaire____::345c9d171ef3c5d706d08041d506428c","value":"Croatian Scientific Bibliography - CROSBI"},"collectedFrom":{"key":"openaire____::345c9d171ef3c5d706d08041d506428c","value":"Croatian Scientific Bibliography - CROSBI"}}],"links":[],"otherTitles":null,"inDiamondJournal":false,"green":false,"isGreen":false,"isInDiamondJournal":false},{"authors":[{"id":null,"fullName":"Mandek Lisica, Denis","name":"Denis","surname":"Mandek Lisica","rank":1,"pid":null},{"id":null,"fullName":"Bubaš, Marija","name":"Marija","surname":"Bubaš","rank":2,"pid":null},{"id":null,"fullName":"Koren, Helena","name":"Helena","surname":"Koren","rank":3,"pid":null},{"id":null,"fullName":"Prašnjak, Anica","name":"Anica","surname":"Prašnjak","rank":4,"pid":null},{"id":null,"fullName":"Bogadi Šare, Ana","name":"Ana","surname":"Bogadi Šare","rank":5,"pid":null},{"id":null,"fullName":"Zavalić, Marija","name":"Marija","surname":"Zavalić","rank":6,"pid":null}],"openAccessColor":null,"publiclyFunded":true,"eoscIfGuidelines":null,"type":"publication","language":{"code":"eng","label":"English"},"countries":[{"code":"HR","label":"Croatia","provenance":null}],"subjects":[{"subject":{"scheme":"FOS","value":"03 medical and health sciences"},"provenance":null},{"subject":{"scheme":"keyword","value":"hospital nurses ; musculoskeletal complaints"},"provenance":null},{"subject":{"scheme":"FOS","value":"0305 other medical science"},"provenance":null},{"subject":{"scheme":"SDG","value":"3. Good health"},"provenance":null}],"mainTitle":"Differences in musculoskeletal complaints and daily functioning in croatian nurses employed in child and adult care – a crown study","subTitle":null,"descriptions":["In 2014 a CROWN (Croatia, Workability, Nurses) study was conducted among Croatian nurses employed in clinical hospitals to determine general health status, physical and psychosocial health of nurses, prevalence and distribution of hand eczema and musculoskeletal symptoms, and their influence on daily functioning. We present the data for musculoskeletal complaints and daily functioning for nurses employed in child and adult care. A Nordic standardised questionnaire for evaluation of musculoskeletal complaints accompanied with Lickert scale for self- evaluation of complaints and a Disability of arm, shoulder and hands (DASH) questionnaire for daily functioning, were used for this part of research in 115 nurses from three large clinical hospitals for children and two large clinical centres for adults. In both groups, the analysis of musculoskeletal pain (sites, frequency) and daily functioning were compared to the duration of work experience, the number of patients, patients’ weight and nurses’ general health. The prevalence rate of musculoskeletal complaints among our cohorts of nurses was 95% in childcare, and 98, 6% in adult care. Lower back pain and neck pain were the most frequent complaints in both groups. The lower back pain had the strongest influence on daily functioning. The prevalence rate for musculoskeletal complaints in this study was very high, higher than reported in similar other studies. That has confirmed the great need for analysing reasons for such a high prevalence of complaints and taking actions which will reduce their contributing factors and influence on daily functioning. 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Clean energy"},"provenance":null}],"mainTitle":"Editorial to Sensors Special Issue „Vibration Energy Harvesting for Wireless Sensors“","subTitle":null,"descriptions":["Mechanical vibrations occur in the operation of most technical systems. High-level vibrations could indicate an overloaded or damaged technical system. These states and behaviours can be monitored or reported, and ambient vibrations may, in turn, be used as a source of energy. The vibrational energy harvesters used in this framework could be an alternative to the supply of low-power autonomous electronic systems for the remote sensing of operations. However, the level of energy harvested using such an approach is usually very low, and the whole concept of vibration energy harvesting system operations (including power management electronics and wireless sensors) must be adapted for specific target applications. This Special Issue, through twelve diverse contributions, intends to present some of the contemporary challenges, solutions and insights around the outlined issues and provides an overview of this rapidly evolving topic. The papers collected in this SI cover a variety of energy harvesting sources, as well as the need to create bases of numerical and experimental evidence around them. Qualifying and quantifying their performances in terms of energy harvesting levels, as well as their consistency and potential applications, are all reflected in these papers. 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